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rabbit polyclonal anti muc21 antibody  (Novus Biologicals)


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    Novus Biologicals rabbit polyclonal anti muc21 antibody
    Fig. 1. Papanicolaou staining in liquid-based cytology (LBC) samples and BRD4, c-MYC, TP53, and <t>MUC21</t> immunohistochemical study in oral cytological samples: (A) NILM, (B) LSIL, (C) HSIL, and (D) SCC. (E-H) BRD4 immunocytochemical staining. Although BRD4 staining was generally negative in (E) NILM samples, (F) positive nuclear staining was observed in LSIL, (G) HSIL, and (H) SCC samples. (I-L) c-MYC immunocytochemical staining. Although c-MYC staining was generally negative in (I) NILM samples, positive nuclear staining was observed in (J) LSIL, (K) HSIL, and (L) SCC samples. (M-P) TP53 immunocytochemical staining. Although TP53 staining was generally negative in (M) NILM, (N) LSIL, and (O) HSIL samples, positive nuclear staining was observed in (P) SCC samples. (Q-T) MUC21 immunocytochemical staining. Although MUC21 staining was generally positive in (M) NILM and (N) LSIL, negative cytoplasmic staining was observed in (O) HSIL and (T) SCC samples. Original magnification, 400 x. Scale bars, 20 µm. NILM, negative for intraepithelial lesion or malignancy; LSIL, low‑grade squamous intra epithelial lesion; HSIL, high‑grade squamous intraepithelial lesion; SCC, squamous cell carcinoma.
    Rabbit Polyclonal Anti Muc21 Antibody, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 93/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit polyclonal anti muc21 antibody/product/Novus Biologicals
    Average 93 stars, based on 6 article reviews
    rabbit polyclonal anti muc21 antibody - by Bioz Stars, 2026-06
    93/100 stars

    Images

    1) Product Images from "Searching for new early detection markers of OED and oral SCC using oral liquid-based cytology"

    Article Title: Searching for new early detection markers of OED and oral SCC using oral liquid-based cytology

    Journal: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology

    doi: 10.1016/j.ajoms.2023.11.007

    Fig. 1. Papanicolaou staining in liquid-based cytology (LBC) samples and BRD4, c-MYC, TP53, and MUC21 immunohistochemical study in oral cytological samples: (A) NILM, (B) LSIL, (C) HSIL, and (D) SCC. (E-H) BRD4 immunocytochemical staining. Although BRD4 staining was generally negative in (E) NILM samples, (F) positive nuclear staining was observed in LSIL, (G) HSIL, and (H) SCC samples. (I-L) c-MYC immunocytochemical staining. Although c-MYC staining was generally negative in (I) NILM samples, positive nuclear staining was observed in (J) LSIL, (K) HSIL, and (L) SCC samples. (M-P) TP53 immunocytochemical staining. Although TP53 staining was generally negative in (M) NILM, (N) LSIL, and (O) HSIL samples, positive nuclear staining was observed in (P) SCC samples. (Q-T) MUC21 immunocytochemical staining. Although MUC21 staining was generally positive in (M) NILM and (N) LSIL, negative cytoplasmic staining was observed in (O) HSIL and (T) SCC samples. Original magnification, 400 x. Scale bars, 20 µm. NILM, negative for intraepithelial lesion or malignancy; LSIL, low‑grade squamous intra epithelial lesion; HSIL, high‑grade squamous intraepithelial lesion; SCC, squamous cell carcinoma.
    Figure Legend Snippet: Fig. 1. Papanicolaou staining in liquid-based cytology (LBC) samples and BRD4, c-MYC, TP53, and MUC21 immunohistochemical study in oral cytological samples: (A) NILM, (B) LSIL, (C) HSIL, and (D) SCC. (E-H) BRD4 immunocytochemical staining. Although BRD4 staining was generally negative in (E) NILM samples, (F) positive nuclear staining was observed in LSIL, (G) HSIL, and (H) SCC samples. (I-L) c-MYC immunocytochemical staining. Although c-MYC staining was generally negative in (I) NILM samples, positive nuclear staining was observed in (J) LSIL, (K) HSIL, and (L) SCC samples. (M-P) TP53 immunocytochemical staining. Although TP53 staining was generally negative in (M) NILM, (N) LSIL, and (O) HSIL samples, positive nuclear staining was observed in (P) SCC samples. (Q-T) MUC21 immunocytochemical staining. Although MUC21 staining was generally positive in (M) NILM and (N) LSIL, negative cytoplasmic staining was observed in (O) HSIL and (T) SCC samples. Original magnification, 400 x. Scale bars, 20 µm. NILM, negative for intraepithelial lesion or malignancy; LSIL, low‑grade squamous intra epithelial lesion; HSIL, high‑grade squamous intraepithelial lesion; SCC, squamous cell carcinoma.

    Techniques Used: Staining, Immunohistochemical staining

    Fig. 2. Histopathological and immunohistochemical expressions patterns of BRD4, c‑MYC, TP53, and MUC21 in normal epithelium (NOE), hyperplasia (HYP), oral epithelial dysplasia (OED), and squamous cell carcinoma (SCC) samples. (A, E, I, M, Q) NOE, (B, F, J, N, R) HYP, (C, G, K, O, S) OED and (D, H, L, P, T) SCC. (A-D) Hematoxylin and eosin (H&E), (E-H) BRD4, (I-L) c-MYC, (M-P) TP53, and (Q-T) MUC21. Original magnification, 100x. Scale bars, 100 µm.
    Figure Legend Snippet: Fig. 2. Histopathological and immunohistochemical expressions patterns of BRD4, c‑MYC, TP53, and MUC21 in normal epithelium (NOE), hyperplasia (HYP), oral epithelial dysplasia (OED), and squamous cell carcinoma (SCC) samples. (A, E, I, M, Q) NOE, (B, F, J, N, R) HYP, (C, G, K, O, S) OED and (D, H, L, P, T) SCC. (A-D) Hematoxylin and eosin (H&E), (E-H) BRD4, (I-L) c-MYC, (M-P) TP53, and (Q-T) MUC21. Original magnification, 100x. Scale bars, 100 µm.

    Techniques Used: Immunohistochemical staining

    Fig. 4. The correlation between the labeling index and the relative mRNA levels of each marker (BRD4, c-MYC, TP53, and MUC21) in the oral cytological specimens. These markers displayed significant positive correlations: (A) BRD4 (R= 0.781, p < 0.01), (B) c‑MYC (R=0.807, p < 0.01), (C) TP53 (R=0.606, p < 0.01), and (D) MUC21 (R=0.514, p < 0.05).
    Figure Legend Snippet: Fig. 4. The correlation between the labeling index and the relative mRNA levels of each marker (BRD4, c-MYC, TP53, and MUC21) in the oral cytological specimens. These markers displayed significant positive correlations: (A) BRD4 (R= 0.781, p < 0.01), (B) c‑MYC (R=0.807, p < 0.01), (C) TP53 (R=0.606, p < 0.01), and (D) MUC21 (R=0.514, p < 0.05).

    Techniques Used: Labeling, Marker

    Fig. 5. Receiver operating characteristic analysis for LSIL or higher category specimens were screened using BRD4 (red line), c-MYC (green line), MUC21 (brown line), and TP53 (blue line) as candidate markers. The optimal cut-off values of each markers were calculated using ‘closest-topleft’ (10, 28).
    Figure Legend Snippet: Fig. 5. Receiver operating characteristic analysis for LSIL or higher category specimens were screened using BRD4 (red line), c-MYC (green line), MUC21 (brown line), and TP53 (blue line) as candidate markers. The optimal cut-off values of each markers were calculated using ‘closest-topleft’ (10, 28).

    Techniques Used:



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    rabbit polyclonal anti muc21 antibody  (Novus Biologicals)
    93
    Novus Biologicals rabbit polyclonal anti muc21 antibody
    Fig. 1. Papanicolaou staining in liquid-based cytology (LBC) samples and BRD4, c-MYC, TP53, and <t>MUC21</t> immunohistochemical study in oral cytological samples: (A) NILM, (B) LSIL, (C) HSIL, and (D) SCC. (E-H) BRD4 immunocytochemical staining. Although BRD4 staining was generally negative in (E) NILM samples, (F) positive nuclear staining was observed in LSIL, (G) HSIL, and (H) SCC samples. (I-L) c-MYC immunocytochemical staining. Although c-MYC staining was generally negative in (I) NILM samples, positive nuclear staining was observed in (J) LSIL, (K) HSIL, and (L) SCC samples. (M-P) TP53 immunocytochemical staining. Although TP53 staining was generally negative in (M) NILM, (N) LSIL, and (O) HSIL samples, positive nuclear staining was observed in (P) SCC samples. (Q-T) MUC21 immunocytochemical staining. Although MUC21 staining was generally positive in (M) NILM and (N) LSIL, negative cytoplasmic staining was observed in (O) HSIL and (T) SCC samples. Original magnification, 400 x. Scale bars, 20 µm. NILM, negative for intraepithelial lesion or malignancy; LSIL, low‑grade squamous intra epithelial lesion; HSIL, high‑grade squamous intraepithelial lesion; SCC, squamous cell carcinoma.
    Rabbit Polyclonal Anti Muc21 Antibody, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rabbit polyclonal anti muc21 antibody/product/Novus Biologicals
    Average 93 stars, based on 1 article reviews
    rabbit polyclonal anti muc21 antibody - by Bioz Stars, 2026-06
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Fig. 1. Papanicolaou staining in liquid-based cytology (LBC) samples and BRD4, c-MYC, TP53, and MUC21 immunohistochemical study in oral cytological samples: (A) NILM, (B) LSIL, (C) HSIL, and (D) SCC. (E-H) BRD4 immunocytochemical staining. Although BRD4 staining was generally negative in (E) NILM samples, (F) positive nuclear staining was observed in LSIL, (G) HSIL, and (H) SCC samples. (I-L) c-MYC immunocytochemical staining. Although c-MYC staining was generally negative in (I) NILM samples, positive nuclear staining was observed in (J) LSIL, (K) HSIL, and (L) SCC samples. (M-P) TP53 immunocytochemical staining. Although TP53 staining was generally negative in (M) NILM, (N) LSIL, and (O) HSIL samples, positive nuclear staining was observed in (P) SCC samples. (Q-T) MUC21 immunocytochemical staining. Although MUC21 staining was generally positive in (M) NILM and (N) LSIL, negative cytoplasmic staining was observed in (O) HSIL and (T) SCC samples. Original magnification, 400 x. Scale bars, 20 µm. NILM, negative for intraepithelial lesion or malignancy; LSIL, low‑grade squamous intra epithelial lesion; HSIL, high‑grade squamous intraepithelial lesion; SCC, squamous cell carcinoma.

    Journal: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology

    Article Title: Searching for new early detection markers of OED and oral SCC using oral liquid-based cytology

    doi: 10.1016/j.ajoms.2023.11.007

    Figure Lengend Snippet: Fig. 1. Papanicolaou staining in liquid-based cytology (LBC) samples and BRD4, c-MYC, TP53, and MUC21 immunohistochemical study in oral cytological samples: (A) NILM, (B) LSIL, (C) HSIL, and (D) SCC. (E-H) BRD4 immunocytochemical staining. Although BRD4 staining was generally negative in (E) NILM samples, (F) positive nuclear staining was observed in LSIL, (G) HSIL, and (H) SCC samples. (I-L) c-MYC immunocytochemical staining. Although c-MYC staining was generally negative in (I) NILM samples, positive nuclear staining was observed in (J) LSIL, (K) HSIL, and (L) SCC samples. (M-P) TP53 immunocytochemical staining. Although TP53 staining was generally negative in (M) NILM, (N) LSIL, and (O) HSIL samples, positive nuclear staining was observed in (P) SCC samples. (Q-T) MUC21 immunocytochemical staining. Although MUC21 staining was generally positive in (M) NILM and (N) LSIL, negative cytoplasmic staining was observed in (O) HSIL and (T) SCC samples. Original magnification, 400 x. Scale bars, 20 µm. NILM, negative for intraepithelial lesion or malignancy; LSIL, low‑grade squamous intra epithelial lesion; HSIL, high‑grade squamous intraepithelial lesion; SCC, squamous cell carcinoma.

    Article Snippet: All slides were subjected to antigen retrieval using 10 mM Tris-HCl, 1 mM EDTA-2Na (pH8.0) in a microwave oven of 1000 W for 20 min, followed by incubation with a rabbit polyclonal anti-TP53 antibody (1:50 dilution; clone ab131442; Abcam, Cambridge, MA, USA), a rabbit monoclonal anti-cMYC antibody (1:100 dilution; clone ab32072; Abcam), a rabbit polyclonal anti-MUC21 antibody (1:200 dilution; clone NBP2–31023; Novus), or a rabbit monoclonal anti-BRD4 antibody (1:100 dilution; clone ab128874; Abcam).

    Techniques: Staining, Immunohistochemical staining

    Fig. 2. Histopathological and immunohistochemical expressions patterns of BRD4, c‑MYC, TP53, and MUC21 in normal epithelium (NOE), hyperplasia (HYP), oral epithelial dysplasia (OED), and squamous cell carcinoma (SCC) samples. (A, E, I, M, Q) NOE, (B, F, J, N, R) HYP, (C, G, K, O, S) OED and (D, H, L, P, T) SCC. (A-D) Hematoxylin and eosin (H&E), (E-H) BRD4, (I-L) c-MYC, (M-P) TP53, and (Q-T) MUC21. Original magnification, 100x. Scale bars, 100 µm.

    Journal: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology

    Article Title: Searching for new early detection markers of OED and oral SCC using oral liquid-based cytology

    doi: 10.1016/j.ajoms.2023.11.007

    Figure Lengend Snippet: Fig. 2. Histopathological and immunohistochemical expressions patterns of BRD4, c‑MYC, TP53, and MUC21 in normal epithelium (NOE), hyperplasia (HYP), oral epithelial dysplasia (OED), and squamous cell carcinoma (SCC) samples. (A, E, I, M, Q) NOE, (B, F, J, N, R) HYP, (C, G, K, O, S) OED and (D, H, L, P, T) SCC. (A-D) Hematoxylin and eosin (H&E), (E-H) BRD4, (I-L) c-MYC, (M-P) TP53, and (Q-T) MUC21. Original magnification, 100x. Scale bars, 100 µm.

    Article Snippet: All slides were subjected to antigen retrieval using 10 mM Tris-HCl, 1 mM EDTA-2Na (pH8.0) in a microwave oven of 1000 W for 20 min, followed by incubation with a rabbit polyclonal anti-TP53 antibody (1:50 dilution; clone ab131442; Abcam, Cambridge, MA, USA), a rabbit monoclonal anti-cMYC antibody (1:100 dilution; clone ab32072; Abcam), a rabbit polyclonal anti-MUC21 antibody (1:200 dilution; clone NBP2–31023; Novus), or a rabbit monoclonal anti-BRD4 antibody (1:100 dilution; clone ab128874; Abcam).

    Techniques: Immunohistochemical staining

    Fig. 4. The correlation between the labeling index and the relative mRNA levels of each marker (BRD4, c-MYC, TP53, and MUC21) in the oral cytological specimens. These markers displayed significant positive correlations: (A) BRD4 (R= 0.781, p < 0.01), (B) c‑MYC (R=0.807, p < 0.01), (C) TP53 (R=0.606, p < 0.01), and (D) MUC21 (R=0.514, p < 0.05).

    Journal: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology

    Article Title: Searching for new early detection markers of OED and oral SCC using oral liquid-based cytology

    doi: 10.1016/j.ajoms.2023.11.007

    Figure Lengend Snippet: Fig. 4. The correlation between the labeling index and the relative mRNA levels of each marker (BRD4, c-MYC, TP53, and MUC21) in the oral cytological specimens. These markers displayed significant positive correlations: (A) BRD4 (R= 0.781, p < 0.01), (B) c‑MYC (R=0.807, p < 0.01), (C) TP53 (R=0.606, p < 0.01), and (D) MUC21 (R=0.514, p < 0.05).

    Article Snippet: All slides were subjected to antigen retrieval using 10 mM Tris-HCl, 1 mM EDTA-2Na (pH8.0) in a microwave oven of 1000 W for 20 min, followed by incubation with a rabbit polyclonal anti-TP53 antibody (1:50 dilution; clone ab131442; Abcam, Cambridge, MA, USA), a rabbit monoclonal anti-cMYC antibody (1:100 dilution; clone ab32072; Abcam), a rabbit polyclonal anti-MUC21 antibody (1:200 dilution; clone NBP2–31023; Novus), or a rabbit monoclonal anti-BRD4 antibody (1:100 dilution; clone ab128874; Abcam).

    Techniques: Labeling, Marker

    Fig. 5. Receiver operating characteristic analysis for LSIL or higher category specimens were screened using BRD4 (red line), c-MYC (green line), MUC21 (brown line), and TP53 (blue line) as candidate markers. The optimal cut-off values of each markers were calculated using ‘closest-topleft’ (10, 28).

    Journal: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology

    Article Title: Searching for new early detection markers of OED and oral SCC using oral liquid-based cytology

    doi: 10.1016/j.ajoms.2023.11.007

    Figure Lengend Snippet: Fig. 5. Receiver operating characteristic analysis for LSIL or higher category specimens were screened using BRD4 (red line), c-MYC (green line), MUC21 (brown line), and TP53 (blue line) as candidate markers. The optimal cut-off values of each markers were calculated using ‘closest-topleft’ (10, 28).

    Article Snippet: All slides were subjected to antigen retrieval using 10 mM Tris-HCl, 1 mM EDTA-2Na (pH8.0) in a microwave oven of 1000 W for 20 min, followed by incubation with a rabbit polyclonal anti-TP53 antibody (1:50 dilution; clone ab131442; Abcam, Cambridge, MA, USA), a rabbit monoclonal anti-cMYC antibody (1:100 dilution; clone ab32072; Abcam), a rabbit polyclonal anti-MUC21 antibody (1:200 dilution; clone NBP2–31023; Novus), or a rabbit monoclonal anti-BRD4 antibody (1:100 dilution; clone ab128874; Abcam).

    Techniques: